Yes, fully compatible. It was tested and certified for Windows 11 21H2 and later. For Windows 11 24H2, consider updating to chipset driver 6.x series which includes SMBus 5.12.0.45 or higher.
The specific driver version is frequently cited in technical forums and AMD release notes. While driver versions increment rapidly, this specific build is notable for a few key reasons: amd smbus driver 5.12.0.38
Regulating power distribution and enabling sleep/hibernation states. Yes, fully compatible