: Plug the USB cable back in and turn on the plotter. Windows should now recognize it as a "USB Serial Port". Verify in Device Manager : Right-click the Start menu and select Device Manager .
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Another program (like a previous instance of your cutter software) is using the port. Close all cutting software. Restart your computer. First, open only the cutting program and send the cut. : Plug the USB cable back in and turn on the plotter