HDR-P-Micro sensors often utilize a . Mimicking the human eye, these sensors compress the bright end of the spectrum. As light intensity increases, the signal output increases at a slower rate. This allows the sensor to capture incredibly bright lights without saturation while retaining detail in the shadows, all in a single exposure.

The "P" refers to . Standard microscopes suffer from stage drift and thermal expansion. HDR-P-Micro employs real-time fiducial tracking. The system uses infrared beacons embedded in the coverslip to mathematically correct for XY and Z drift every 100 milliseconds.

| Technology | Resolution | Live Sample? | Speed (FPS) | Cost | Dynamic Range | | :--- | :--- | :--- | :--- | :--- | :--- | | | 250 nm | Yes | 50 | $5k | 60 dB | | Confocal | 180 nm | Yes (slow) | 1 | $50k | 70 dB | | STED (Super-res) | 30 nm | Rarely | 0.5 | $500k | 65 dB | | HDR-P-Micro | 50 nm | Yes | 30 | $75k | 120 dB |