Gone is the familiar suburban house. "Time to Wake Up" typically transports players to an abandoned medical facility or a mental institution. The sterile, white corridors and flickering lights create a different atmosphere of dread compared to the creaky floorboards of the original house.

While previous games focused on sheer hiding, "Time to Wake Up" introduces an aggressive AI. Granny learns from your previous attempts. If you hid in the wardrobe on Day 1, she will check the wardrobe immediately on Day 2.