Cheat Engine Diablo 2 Resurrected Hot! Link

Because you edit the file on disk, you can then launch D2R offline normally. Blizzard never sees it unless you try to move that character online (don’t).

If you just want to theorycraft a build without playing, use online planners. They simulate skills, breakpoints, and damage without any risk. Cheat Engine Diablo 2 Resurrected